New Covid research factors to long-term mind tissue loss, warns Dr. Scott Gottlieb

Dr. Scott Gottlieb warned on Thursday of the potential for long-term brain loss related to Covid, citing a new study from the UK.

“In short, the study suggests that there could be long-term loss of brain tissue from Covid, and that would have some long-term consequences,” said the former FDA chief and CNBC employee.

“You could compensate for that over time, so the symptoms of it may go away, but you will never get the tissue back if the virus actually destroys it,” said Gottlieb, serving on the board of Covid vaccine maker Pfizer.

The UK study looked at brain imaging before and after coronavirus infection, specifically looking at the potential effects on the nervous system.

Gottlieb told CNBC’s “The News with Shepard Smith” that the destruction of brain tissue could explain why Covid patients have lost their sense of smell.

“The decrease in the amount of cortical tissue happened by chance in regions of the brain that are near the places responsible for the odor,” he said. “What it suggests is that the odor, the loss of smell, is just an effect of a more primary process that is going on, and that process is actually the shrinking of the cortical tissue.”

Disclosure: Scott Gottlieb is a CNBC employee and a member of the board of directors of Pfizer, genetic testing startup Tempus, health technology company Aetion Inc., and biotechnology company Illumina.

Journey app presents skittish vacationers 60-day freeze on lodge charges

Two views of the Hopper app’s new Price Freeze feature, showing (left) a step in the search process and (right) a list of active freezes.

Hopper

After a year of lockdown and limited travel, Americans want flexibility and freedom when planning trips.

They got used to it during the coronavirus pandemic, as travel suppliers scrambled to adjust to both market and medical realities in spring and summer of last year by introducing not only new health and safety protocols but looser rebooking and cancellation policies, as well.

Many of the changes are here to stay.

“Airlines and hotels, so many of them are still offering flexible booking options,” said travel advisor Mike Rubinstein, owner and director of UprouteMe in Los Angeles. “And while airfares aren’t as insanely inexpensive as they were a few months ago, there are really still some great flight deals out there — and fantastic hotel rates to be had, too.”

To capitalize on that zeitgeist while helping travelers lock in some of those great hotel prices, travel app Hopper rolled out its new “Price Freeze for Hotels” feature on Wednesday. The feature lets users lock in the best rate at a specific hotel for up to 60 days.

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Price trumps pandemic fears as Americans book travel again
Sun Belt beach, city stays top travelers summer wish lists

If the nightly rate increases during the freeze window, Hopper will cover up to $100 of total stay cost to help keep the rate lower. If prices drop, users pay the new lower rate.

“Hotels don’t actually take on the risk; Hopper underwrites it,” said Anwesha Bhattacharjee, head of hotel fintech at Hopper. “When you’re coming onto Hopper, we’ll guarantee the price point for you.”

Users place a deposit that’s determined by an algorithm that factors in trip length and the likelihood of price changes in a given market, said Bhattacharjee.

When they’re ready to book their room at the rate they froze, their deposit is credited to the booking price. (An actual room is not reserved until they do so, despite the rate freeze.) If they want to change hotels, the freeze and deposit are transferrable to a new booking.

Hopper estimates that for the typical two- to three-night booking, Price Freeze users save an average $17 per night and $43 per stay. “But we’ve seen customers save $100, or in the high $80s,” she noted.

Accommodation rates look like they’ll only keep rising, according to Boston- and Montreal-based Hopper, which has tracked a 130% jump in hotel searches since the beginning of 2021, increasing by 7% weekly.

Thanks to leaps in seasonal and domestic travel demand, nightly rates will likely rise 17%, to $165 on average nationwide, by early July, Hopper said. “Users will always end up saving money by using Price Freeze,” said Bhattacharjee.

Price-locks for online airfares have been around for a number of years.

“As we entered the pandemic, we realized that a lot of our customers were feeling a lot of anxiety around not being able to commit to travel because they didn’t know which locations would close down or open up, or what the quarantine rules would be,” Bhattacharjee noted.

“A 14- or 21-day freeze wasn’t what they were looking for so we started out offering a longer price freeze duration precisely for that,” she added. “We knew our customers were feeling they wanted to travel but couldn’t make up their minds just yet and need some more time.”

Price Freeze is particularly helpful for large groups and families planning travel together, when multiple OKs are required on rates before committing to a hotel stay, Bhattacharjee said.

“That need is not going to go away,” pandemic or no pandemic, she noted. “A lot of our customers also like the option to defer payment,” a side benefit of Price Freeze functionality.

Hopper says it’s the largest North American travel app, with more than 50 million downloads and $1.2 billion in sales of travel and travel-related product in the past year from 2 million hotels, 300 airlines and a selection of car rental partners.

Hopper is next developing functionality that will allow users to select the bed configurations they want (e.g., doubles, queen, king) when freezing rates, said Bhattacharjee. Price Freeze for Hotels is available on both iOS and Android versions of Hopper and anywhere the app operates.

Kylie Jenner explains the place she stands four years after breaking apart with Tyga

Kardashians Reunion Recap Pt. 1: “KUWTK” supplement (S20, Ep13)

These exes certainly don’t keep up with each other.

During the first part of the Reunion Keeping Up With the Kardashians, which will air tonight June 17th on E! was broadcast, Kylie Jenner revealed where she stands with her ex-boyfriend Tyga. While the lip smock mogul made it clear that there was no bad blood between her and the “Taste” rapper, they are by no means close.

“We’re not friends,” revealed the mother of a reunification guest Andy Cohen. “But we are fine. When I see him outside or meet him somewhere, you know I always wish him well. I don’t have bad feelings towards him. “

As E! The news readers know well that Kylie and Tyga started dating in October 2014, but went through some ups and downs during their romance. In November 2015, E! News sources revealed that the couple briefly broke up before getting back together less than a week later.

The KUWTK star confirmed she was back with Tyga during an appearance on the Ellen DeGeneres Show. “No, honestly people got it all wrong,” she said at the time. “No. We’re not separate.”

Leisure business will get well from Covid

BEIJING – Chinese dancer and TV presenter Jin Xing is confident that the entertainment industry will return to normal and that the arts will be more valued after the pandemic.

In China, where tight lockdowns helped control the domestic spread of Covid-19 within months, Jin’s private dance company resumed national touring last year, she told Tania Bryer at the CNBC Evolve Global Summit.

The troops are now in “very good condition,” said Jin. She expects all of China’s theaters to open this year, followed by live stadium concerts.

While most of China has resumed normal business activity for more than a year, the country has had to deal with small coronavirus outbreaks, most recently in the southern export hub of Guangzhou City. The uncertainty and the continued spread of the virus abroad have contributed to a subdued recovery in Chinese consumer spending.

Jin has seen the ups and downs of China’s development since the 1960s.

She became an award-winning military dancer as a teenager, then enjoyed similar success as a dancer in New York before returning to China. Jin is best known today as China’s earliest open transgender star who also hosts television shows.

Audience becomes “super calm”

In the wake of the pandemic, new protocols like virus testing and face masks have created a new dynamic between performers and their audience – especially when they’re allowed to meet offline instead of online.

Jin Xing (in red) appears for the first time in over 20 years and for the first time ever as a woman during a dress rehearsal on January 31, 2012, before it opens at the Joyce Theater.

Timothy A. Clary | AFP | Getty Images

At a recent performance in Nanjing City, near Shanghai, all 1,900 spectators wore masks, Jin said.

That meant the audience was “super calm” and “focused on what was happening” rather than chatting to each other, she said. That creates a “fantastic” environment for an artist on stage, she added.

Another TV show starts

Jin is also enjoying success with young people online.

This spring, the first season of their reality TV dating show “Ni hao ling yi ban” aired on the video platform iQiyi. The show’s name roughly translates to “Hello, (my) other half” and focuses on Chinese people who graduated from top foreign universities before becoming entrepreneurs in China.

“They are doing very well professionally. But there is still (a) huge void in their personal lives,” said Jin, noting that regardless of their education, participants are faced with the same question of what kind of family to raise.

Read more about China from CNBC Pro

The matchmaking show is slated for another season later this year, she told CNBC.

Whether on stage or online, Jin hopes her work can help keep viewers calm, especially after the shock of the pandemic.

People can never make enough money, she said, but people can “slow down”.

Financial institution of Japan financial coverage assertion forward

SINGAPORE — Shares in Asia-Pacific looked set for a mixed start on Friday following an overnight drop for the Dow Jones Industrial Average on Wall Street.

Futures pointed to a higher open for Japanese stocks. The Nikkei futures contract in Chicago was at 29,195 while its counterpart in Osaka was at 29,130. That compared against the Nikkei 225’s last close at 29,018.33.

Meanwhile, shares in Australia looked poised for an opening dip. The SPI futures contract was at 7,305, against the S&P/ASX 200’s last close at 7,359.

Looking ahead, the Bank of Japan is expected to release its statement on monetary policy on Friday, including its interest rate decision.

Overnight on Wall Street, the Dow Jones Industrial Average fell 210.22 points to 33,823.45 while the S&P 500 slipped fractionally to 4,221.86. The Nasdaq Composite advanced 0.87% to 14,161.35.

Currencies

The U.S. dollar index, which tracks the greenback against a basket of its peers, was at 91.889 following a recent climb from below 91.

The Japanese yen traded at 110.27 per dollar, stronger than levels above 110.5 against the greenback seen yesterday. The Australian dollar was at $0.7555 as it struggles to recover after declining from above $0.768 earlier this week.

Here’s a look at what’s on tap:

  • Japan: Bank of Japan releases monetary policy statement

Alexis Skyy Says She Doesn’t Settle for Akbar V’s Apology To Her Daughter

alexis skyy akbar v

It’s been a little over two weeks since Alexis Skyy and Akbar V exchanged words on social media. However, Akbar finally took responsibility for her actions and apologized to Alexis Skyy‘s daughter Alaiya. As we previously reported, things took a turn for the worst when Akbar called Alexis’ daughter Alayia ‘braindead.’ Alaiya was born prematurely in January 2018, which resulted in her being diagnosed with a brain condition called Hydrocephalus.

Akbar wrote a lengthy message on her Instagram page saying that she shouldn’t have acted out of character and expressed that she plans to go to therapy to heal. “I want to apologize for my actions a couple of weeks ago. No matter what, I shouldn’t have stepped out of character. I said things I shouldn’t have said.” She continued, “So as a business woman, as a woman, period, I am apologizing for anyone that I offended. I’m better than that, and I’m going to get the help I need and deserve.”

Fans felt that the apology was not genuine and that she should have just taken accountability and gone about her day. Alexis felt the same sentiments as she stepped into The Shade Room and left a comment under the post. “Apology not accepted. Sincerely Alaiya’s mother,” she wrote accompanied with a “100” emoji.

Several Roommates commended Alexis. One Roommate commented, “I don’t blame her. The only reason Akbar is apologizing is because she is getting dragged for even saying it to begin with.”

Neither Akbar nor Alexis made a statement following the apology.

Roommates, leave a comment letting us know what y’all think about this.

Do you want updates directly in your text inbox? Hit us up at 917-722-8057 or https://my.community.com/theshaderoom

BMW begins European take a look at drives with hydrogen gas cell automobiles

A BMW i Hydrogen Next automobile that was photographed in Munich on March 12, 2021.

Andreas Gebert | Bloomberg | Getty Images

The BMW Group has started testing vehicles with hydrogen fuel cell drives. The German automobile giant is testing the technology “under everyday conditions on European roads”.

In an announcement on Wednesday, the company stated that prototypes of the BMW i Hydrogen Next will be tested on a range of metrics such as reliability, safety and efficiency.

It described hydrogen fuel cell technology as “long-term potential to complement internal combustion engines, plug-in hybrid systems and battery-electric vehicles”.

According to BMW, the technology could “become an attractive alternative to battery-electric drives – especially for customers who do not have their own access to the electric charging infrastructure or who frequently drive long distances.” The tests should lead to the production of a small series model in 2022.

Read more about clean energy from CNBC Pro

Toyota supplies the individual cells of the vehicles, while BMW develops the fuel cell stack and the complete drive system. The hydrogen tank of the BMW i Hydrogen Next can be filled in three to four minutes and offers the driver “a range of several hundred kilometers in any weather”.

Described by the International Energy Agency as a “versatile energy carrier”, hydrogen has a wide range of possible uses and can be used in sectors such as industry and transport.

BMW is one of several automotive companies researching the potential of hydrogen and the idea of ​​using it in a vehicle is not new.

As early as November 2006, the company announced that production of the BMW Hydrogen 7 had started and described the vehicle as “the world’s first hydrogen-powered luxury sedan”. The Hydrogen 7, he added, used an internal combustion engine and could run on gasoline (gasoline) or liquid hydrogen.

Jaguar Land Rover recently announced Tuesday that it was working on a prototype hydrogen fuel cell electric vehicle, with testing of the concept scheduled to begin later this year.

The vehicle is based on the company’s new version of the company’s Land Rover Defender and is part of JLR’s broader effort to meet its goal of zero tailpipe emissions by 2036. The tests will focus on areas such as fuel economy and off-road capability.

Other manufacturers that have entered the hydrogen fuel cell market include Toyota and Honda, while smaller companies like Riversimple are also working on hydrogen-powered cars.

This week, Volvo Cars also announced that it is partnering with SSAB, a Sweden-based steel maker, to “collaborate on the development of fossil-free, high-quality steel for use in the automotive industry”.

According to Volvo Cars, the collaboration will focus, among other things, on an SSAB initiative called Hybrit, which was founded together with the energy company Vattenfall and the iron ore producing LKAB.

According to Volvo Cars, the goal of the Hybrit project is “to replace coking coal, which is traditionally used in iron ore-based steelmaking, with fossil-free electricity and hydrogen.”

The genetic testing firm 23andMe is buying and selling increased after the merger with Branson SPAC

Anne Wojcicki, co-founder and CEO of 23andMe (right) celebrates with 23andMe employees after remotely ringing the NASDAQ opening bell at the headquarters of DNA technology company 23andMe in Sunnyvale, California, USA on June 17, 2021.

Peter DaSilva | Reuters

The newest trade on the exchange is “ME”.

23andMe, a personalized medicine and home genetic test kit company, went public on Thursday through a merger with a Richard Branson SPAC, VG Acquisition Corp..

23andMe stock rose 21% on the Nasdaq on its first day of trading as a publicly traded company.

Founded by Anne Wojcicki – the former wife of Google founder Sergey Brin who was an early investor in the company – 23andMe was founded 15 years ago. Together with Ancestry, it helped advance the idea that genetic testing is not just a medical field, but a big consumer business. His home test kits, which enabled people to find out their genetic profiles and ancestry by sending some saliva in the mail, ushered in a new era of personalized medicine, albeit not without controversy.

23andMe, a four-time CNBC Disruptor 50 company, had no straight or sure path to success as a publicly traded company.

It was reviewed by the FDA earlier in its history; Questions about consumer privacy continue to arise as genetic information is collected from millions of people; has run into financial difficulties in recent years when the market for personalized genetic testing seemed saturated; Skepticism about the basis of their gene-based risk analysis remains controversial; and as it delves deeper into drug development, a gap in its current customer base and underlying genetic data between a mostly European genetic profile and an underrepresentation of many minorities and ethnic groups.

“It will take time … to really make sure we get all communities to participate in the research,” Wojcicki said Thursday morning in an interview with CNBC’s TechCheck. “You can’t make discoveries in a population if those people aren’t part of it. We need the right customers and we have to present the product to them in the right way.”

Wojcicki says the company has big things ahead of it for both its consumer and drug discovery and development platforms. Approximately 80% of 23andMe’s 11 million members now choose to share their genetic information (anonymized) for drug development research.

“Our genetics represent all of life on this planet and we have the opportunity to understand what it means and, in doing so, it will improve your own life, but it will also contribute to all kinds of research discoveries,” said Wojcicki.

She says the controversy over the medical usefulness of the information won’t go away once it is put into the hands of consumers, and it ranges from critical, clinical information such as mutations in the gene that causes breast cancer, BRCA, to “more controversial” genetic ones Information on variants of Alzheimer’s disease. Some people at higher risk of blood clots choose to walk around more during flights based on their 23andMe reports.

However, she added that consumers have shown that they want this information to help them make decisions.

In the case of Alzheimer’s risk, she said, “This information … really affects how they live their lives … how they retire … plan to get older.”

Her own 10-year-old son used the company’s lactose intolerance analysis to diagnose his abdominal pain, and Wojcicki herself said, although she was reluctant to talk about her personal use of the product, as the daughter of a woman who suffered from breast cancer and who a higher risk of illness, the information influences their decision to drink that “leisure glass of wine”.

“Over the past 15 years we’ve built the infrastructure so we can take off to prove to consumers that we can get the information and understand it without a healthcare professional,” she said.

In her opinion, the key to the future is that consumers want to use the information not only to change their lives, but also to contribute to drug discovery.

23andMe has 40 programs ongoing on its drug discovery platform.

“We want them to have a truly personalized health experience and … benefit the human genome when all of this aggregated data is turned into therapeutic programs,” said Wojcicki. “When I think about the future of therapeutics, the next five years are really about moving these programs forward and getting them into the clinic.”

The company also recently launched a subscription product to bring more content and services to consumers who want to take extra steps after their genetic reports.

“We reach thousands of people who call the customer care team each week and want to know how this information can be used and applied to lead healthier longer lives,” she said.

The IPO market already set an annual record for the transaction volume of $ 171 billion in 2021, and only halfway through the year. Average first day trading profits on trades this year were over 40%. Although both the traditional IPO market and SPAC yields have cooled in recent months, the Renaissance IPO ETF and CNBC SPAC Index have been negative since the start of 2021, with a continuation of last year’s big gains since the start of the year. Meanwhile, concerns about SPAC deals have increased, and some high profile SPACs like Branson’s Virgin Galactic and electric vehicle maker Lordstown Motors have shown high levels of volatility.

Nonetheless, Branson and other investors plan to bring another space company, the satellite internet service Virgin Orbit, to the public via a SPAC in the coming weeks.

This history has been updated for the company’s closing price on the first day of trading on Thursday.

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Meghan McCain and Whoopi Goldberg Get in a Shouting Match Over Biden’s Russia Assembly

Thus far, Joe Biden has received high marks from the press for his recent foreign trip. On Wednesday, though, he did get into a testy exchange with CNN’s Kaitlin Collins.

And the right-wing media has seized on that moment to allude to the entire trip as a disaster. This was the take Meghan McCain took during Thursday’s episode of The View.

The Conservative pundit told her fellow panelists:

“Just because Trump was so bad, it doesn’t absolve Biden’s bad behavior. What he just did was 100 percent Trumpy. I would just like a little intellectual consistency. If Trump had done that, we would be screaming at the top of our lungs one way or another. I just think that I have heard many people in this town, in D.C., talking that the press is getting sick of this. Of how censored he is, who he can and cannot talk to, and then spouting off to her in a way that I found not only unbecoming and ridiculous, but to do it in a foreign country, it was particularly bizarre.”

Whoopi Goldberg jumped into to note that Biden later apologized to Collins. McCain responded, “with all due respect, I don’t care if he’s apologizing. He just embarrassed himself.”

Goldberg shot back, “I don’t care that you don’t care,” and later said to McCain, “you can be how you always are!”

Following a commercial break, the ladies apologized to each other. Watch a clip of the segment below, courtesy of The View:

.@MeghanMcCain on Pres. Biden’s testy response to CNN’s Kaitlan Collins: “Just because Trump was so bad it doesn’t absolve Biden’s bad behavior. What he just did was 100% Trump-y”

“It’s the press’ job to speak truth to power.” pic.twitter.com/239nPjqcRn

— The View (@TheView) June 17, 2021

Todd Neikirk is a New Jersey based politics and technology writer. His work has been featured in psfk.com, foxsports.com and hillreporter.com. He enjoys sports, politics, comic books and spending time at the shore with his family.

President Biden’s July 4th Covid vaccination objectives are in jeopardy

President Joe Biden speaks at the Eisenhower Executive Office Building in Washington, DC, United States on Wednesday, June 2, 2021.

Samuel Corum | Bloomberg | Getty Images

With less than three weeks to Independence Day, President Joe Biden’s recent vaccination goals are in jeopardy.

The country is not on track to meet its two main goals cited in early May: to fully vaccinate 160 million American adults and get 70% of adults in the US at least one vaccination by July 4, according to a CNBC analysis the Centers for Disease control and prevention data.

According to CDC data, around 65% of adults will be at least partially vaccinated by Wednesday. About 13.6 million would have to get their first vaccination over the next 18 days to increase that number to 70%, an average of about 756,000 new vaccinations per day. However, in the US, an average of 336,000 newly vaccinated adults were vaccinated per day per day over the past week.

If the US maintains this last seven-day average, 67% of adults will be at least partially vaccinated by that day.

When asked about the consequences of missing the 70 percent target at a press conference last week, White House chief medical officer Dr. Anthony Fauci said July 4th won’t be the end of the country’s vaccination efforts as the risk of infection and disease persists for those who haven’t been given a chance.

“If you miss the exact target and miss a few percent, it doesn’t mean you stop your vaccination efforts,” said Fauci. “We want to reach 70% of the adult population by July 4th. I think we can, I hope we can, and if we don’t, we will keep moving forward.”

Fauci stressed that people who do not get vaccinated are still at risk. “When you get vaccinated you dramatically, dramatically reduce your risk of infection and almost eliminate your risk of serious illness,” he said.

Fauci, the country’s foremost infectious disease expert, also stressed the importance of vaccination to prevent the Delta variant, first identified in India and quickly becoming the dominant strain in the UK, from establishing itself in the United States.

White House Covid Tsar Jeff Zients told reporters Thursday that the US would pass the 70% mark and “continue to go beyond 70% in the summer months” but did not say whether he expected the country will reach this mark by the target date.

Biden’s goal of 160 million fully vaccinated adults will also be missed if the pace of vaccination does not pick up in the next few weeks. Nearly 142 million adults have completed a vaccination program, and will drop to about 152 million on July 4, assuming the current pace of daily vaccinations reported remains constant.

When Biden first announced the two goals on May 4, the country was well on its way to scoring both. But the vaccination rate has declined in the weeks since, from a seven-day average of 2.2 million vaccinations per day across all ages on the day of the announcement to 1.2 million per day on June 16, according to the CDC.

The White House has redoubled its efforts to increase vaccination rates. Biden announced June as “national month of action,” when his government would mobilize national organizations, community and religious partners, celebrities, athletes and other influential groups to take part in the vaccination campaign. The White House also asked pharmacies to extend their opening hours for the month of June and partnered with Uber and Lyft to offer free trips to vaccination sites.

States are also offering incentives ranging from free beer to $ 1 million worth of lotteries in an attempt to convince Americans to get a prick.

While the statewide rate is still about 5% away, 14 states and the District of Columbia are already past the 70% mark. New York is the last to get there, and Governor Andrew Cuomo announced Tuesday that the state would lift most of its Covid restrictions as a result.

Other states are lagging behind, 22 of which are below the 60% mark. These include Mississippi, Alabama, Louisiana, and Wyoming, each of which less than 50% of its adult residents hit one or more shots.

The U.S. has undoubtedly made strides in fighting Covid, and nationwide case numbers have dropped to levels not seen since the pandemic began, which U.S. officials attribute to the country’s vaccination campaign. American life is closer to pre-pandemic normal than it has been since last March, when the CDC lifted most of its mask recommendations and began easing travel restrictions.

Even so, parts of the US with low vaccination rates pose a risk to the country’s ability to control the pandemic, said Dr. Wafaa El-Sadr, professor of epidemiology and medicine at Columbia University.

“Once you have an unvaccinated population, it is a vulnerable population and in cases it is likely to see an increase,” she said. The constant diffusion means the possibility that new variants will emerge, with the possibility of bypassing the protection provided by vaccines.

“It is valuable to have ambition and very ambitious goals ahead of us, and I think we should do our best to achieve those goals,” said El-Sadr of Biden’s July 4th goals. “If we don’t get there, it doesn’t mean we accept it as a failure and stop doing what we are doing. It means we redouble our efforts.”